Biochemical assays for Multiple Targets

  • Proven track record with Kinases, phosphatases, proteases,lipid metabolic enzymes, epigenetic enzymes, ubiquitinautophagy and SUMO related enzymes,
  • Ligand/receptor, DNA/protein and protein/protein interaction

Focused library screens and hit confirmation

Manage and outsource HTS activities

Support project in Hit to Lead (H2L) and Lead Optimization (LO) Phases

Testing of H2L and LO compounds

  • primary
  • secondary
  • selectivity/profiling assays

Support of Hit Validation

  • Development of compound binding assaysthermal shift or other binding assays
  • Studies of mechanism action for enzyme kinetics, compound reversibility